Hello Arlyn,
To further confuse the issue, many MCF-7 cell lines are contaminated
with non-breast cancer cells. Also, there is an indication, revealed
a couple of years ago, that the MCF-7 cell line never was breast
cancer, but was, instead, ovarian cancer. It was not derived
directly from a breast tumor, but was derived from peritoneal
metastasis in a woman with both cancers.
Go figure.
Keep in mind that in vitro testing of these herbs may not allow for
the mechanism with which they might work in vivo. This could be the
flip side of something working in vitro, and not working in vivo,
which happens all the time.
Mike
Thursday, July 16, 2009, 4:54:04 PM, you wrote:
A> Well, Louise, that was a freakishly complicated conclusion! Here is
A> what it said:
A> RESULTS: Flor-Essence and Essiac herbal tonics at 1%, 2%, 4% and 8%
A> stimulated cell proliferation relative to untreated controls in both
A> estrogen receptor positive (MCF-7 and T47D) and estrogen receptor
A> negative (MDA-MB-231 and MDA-MB-436) cell lines. Exposure to the tonics
A> also produced a dose-dependent increase in ER dependent luciferase
A> activity in MCF-7 cells. A 10(-7) M concentration of ICI 182,780
A> inhibited the induction of ER dependent luciferase activity by
A> Flor-Essence and Essiac, but did not affect cell proliferation.
A> CONCLUSION: Flor-Essence and Essiac Herbal Tonics can stimulate the
A> growth of human breast cancer cells through ER mediated as well as ER
A> independent mechanisms of action.
A> I interpret this as:
A> Cell proliferation happened with both hormone dependent and triple
A> negative cancers.
A> ar
A> [Non-text portions of this message have been removed]
--
Best regards,
Mike mailto:goldenmike@sbcgloba
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